Electroacupuncture reduced periodontal tissue breakdown and the expression of some proinflammatory mediators.
Posted by greenmedinfo on October 7, 2016 8:08 pm
Tags: Animal Study, Anti-Inflammatory Agents, Electroacupuncture, Interleukin-1 beta downregulation, Matrix metalloproteinase-8 (MMP-8) inhibitor, Periodontitis
Categories: Natural Health
J Periodontol. 2015 Jun ;86(6):801-11. Epub 2015 Mar 5. PMID: 25741581
Effects of electroacupuncture on experimental periodontitis in rats.
BACKGROUND: Acupuncture has shown the capability of modulating the immuno-inflammatory response of the host. This study aims to evaluate the effects of electroacupuncture (EA) on ligature-induced periodontitis in rats.METHODS: Thirty-two animals were divided into four groups: 1) control; 2) experimental periodontitis (EP); 3) sham-treated (EP/EA-sham); and 4) treated with EA (EP/EA). For the EP groups, a ligature was placed around the right mandibular first molars at day 1. Sessions of EA or EA-sham were assigned every other day. For EA treatment, large intestine meridian points LI4 and LI11 and stomach meridian points ST36 and ST44 were used. EA-sham was performed in off-meridian points. Animals were euthanized at day 11. Histomorphometric and microtomographic analyses were performed. Immunolabeling patterns for the receptor activator of nuclear factorκB ligand (RANKL), osteoprotegerin (OPG), and tartrate-resistant acid phosphatase (TRAP) were assessed. Expressions of interleukin (IL)-1β, matrix metalloproteinase (MMP)-8, IL-6, and cyclooxygenase (COX)-2 messenger RNAs (mRNAs) were evaluated by quantitative reverse transcription-polymerase chain reaction. Data were analyzed statistically (P
The article, "Electroacupuncture reduced periodontal tissue breakdown and the expression of some proinflammatory mediators.", was syndicated from and first appeared at: http://www.greenmedinfo.com/article/electroacupuncture-reduced-periodontal-tissue-breakdown-and-expression-some-pr.
You may find more great articles by on http://www.greenmedinfo.com/.